About Workshop
This 3-day academic workshop explores the integration of RNA therapeutics, exosome-based drug delivery, and AI-assisted biomedical workflows. Participants will learn how RNA modalities such as siRNA, ASO, circRNA, saRNA, miRNA, and mRNA can be designed and delivered using exosomes and extracellular vesicles as biological nano-carriers.
The workshop combines theory, demonstrations, and hands-on exercises to help learners understand RNA-exosome therapeutic strategies for precision medicine, cancer therapy, genetic disorders, rare diseases, and translational biomedical research.
Aim
To provide participants with a research-oriented understanding of AI-enabled RNA therapeutic design and exosome-based targeted drug delivery, with emphasis on RNA modality selection, extracellular vesicle engineering, therapeutic workflow planning, and translational biomedical applications.
What Participants Will Learn
- To introduce the fundamentals of RNA therapeutics and nucleic acid-based medicine.
- To explain key RNA modalities such as siRNA, ASO, circRNA, saRNA, miRNA, and mRNA.
- To understand the role of exosomes and extracellular vesicles in targeted drug delivery.
- To explore AI-assisted approaches for target identification, literature mining, and therapeutic workflow planning.
- To demonstrate RNA sequence analysis, RNA folding, and secondary structure interpretation.
- To analyze exosome-based cargo loading, source selection, and targeting strategies.
- To connect RNA therapeutic design with exosome-mediated delivery for precision medicine applications.
- To discuss translational, clinical, regulatory, and safety challenges in RNA-exosome therapeutics.
- To help participants develop research-oriented workflows for cancer therapy, genetic disorders, rare diseases, and biomedical applications.
Structure
📅 Day 1: RNA Therapeutics & AI-Assisted Design
- Understanding RNA-based therapeutics and nucleic acid medicine platforms for modern biomedical applications
- Overview of major RNA therapeutic modalities including siRNA, ASO, circRNA, saRNA, miRNA, and mRNA
- Applications of RNA therapeutics in cancer, genetic disorders, viral infections, rare diseases, and precision medicine
- Key challenges in RNA therapeutics including stability, degradation, immune response, off-target effects, and delivery barriers
- AI-assisted target identification, therapeutic candidate screening, and biomedical literature mining
- RNA sequence analysis, secondary structure prediction, and interpretation of therapeutic relevance
- Design considerations for RNA therapeutic optimization and translational development
- Skills gained: RNA therapeutic target analysis, RNA modality selection, literature-based screening, and AI-supported research interpretation
- Tools covered: PubMed, NCBI Gene, RNAcentral, miRBase, RNAfold / ViennaRNA, ChatGPT / Gemini
Hands-on Activity:
- AI-Assisted RNA Therapeutic Target Analysis: Search disease-associated RNA targets using biomedical databases, screen published RNA-based studies, perform basic RNA sequence interpretation, and explore RNA folding and secondary structure prediction workflows
📅 Day 2: Exosome Engineering & Targeted Drug Delivery
- Introduction to exosomes and extracellular vesicles as biological nano-carriers for therapeutic delivery
- Understanding EV biogenesis, cargo transport, and intercellular communication in disease and therapy
- Exosome-mediated delivery of RNA, drugs, proteins, biologics, and advanced therapeutic molecules
- Cargo loading strategies for RNA molecules and therapeutic compounds in exosome-based systems
- Surface engineering and ligand-based targeting approaches for tissue-specific therapeutic delivery
- Applications of exosome delivery in cancer therapy, inflammatory diseases, genetic disorders, regenerative medicine, and precision medicine
- Challenges in EV isolation, purification, characterization, scalability, safety, and clinical translation
- AI applications in exosome cargo prediction, targeting efficiency, delivery optimization, and therapeutic planning
- Skills gained: exosome database exploration, cargo-target mapping, delivery strategy planning, and AI-supported exosome design logic
- Tools covered: ExoCarta, Vesiclepedia, EV-TRACK, PubMed, Google Scholar, BioRender, ChatGPT / Gemini
Hands-on Activity:
- Exosome-Based Therapeutic Delivery Strategy Design: Explore exosome and extracellular vesicle databases, analyze exosome-mediated RNA delivery studies, select exosome source, therapeutic cargo, and target tissue, and develop a conceptual exosome-based RNA or drug delivery strategy
📅 Day 3: Integrated RNA-Exosome Therapeutic Workflow
- Developing an end-to-end RNA-exosome therapeutic workflow for targeted biomedical applications
- Disease target selection, RNA candidate prioritization, and therapeutic relevance assessment
- Selection of suitable RNA modality based on disease mechanism, target biology, and therapeutic objective
- Exosome source selection for targeted RNA, drug, protein, and biologic delivery applications
- Target tissue and cell-type mapping for precision delivery planning and translational workflow design
- AI-guided prediction of RNA stability, toxicity, delivery efficiency, and therapeutic relevance
- Integration of RNA therapeutic design with exosome-based delivery strategies for advanced nanomedicine
- Clinical, manufacturing, scalability, safety, and regulatory considerations for RNA-exosome therapeutics
- Future scope of RNA therapeutics, exosome medicine, nanomedicine, and precision delivery systems
- Skills gained: integrated therapeutic workflow design, RNA-exosome strategy development, disease-target mapping, and translational research planning
- Tools covered: Google Colab, PubMed, NCBI, ExoCarta, Vesiclepedia, RNAcentral, miRBase, RNAfold / ViennaRNA, BioRender, ChatGPT / Gemini
Hands-on Activity:
- AI-Supported RNA-Exosome Therapeutic Workflow Design: Select a disease model, RNA modality, exosome source, and target tissue, then build a conceptual RNA-exosome delivery strategy with key translational challenges and therapeutic relevance
Important Dates
Registration Ends
04:00 PM IST
Workshop Dates
2026-07-27
05:30 PM
05:30 PM
What You Will Gain
Outcomes
- Understand key concepts in RNA therapeutics and nucleic acid-based medicine.
- Differentiate major RNA modalities including siRNA, ASO, circRNA, saRNA, miRNA, and mRNA.
- Explain the role of exosomes and extracellular vesicles in targeted therapeutic delivery.
- Apply AI-assisted approaches for literature mining, target identification, and workflow planning.
- Perform basic RNA sequence analysis and secondary structure interpretation.
- Analyze exosome-based cargo delivery and targeting strategies.
- Design a conceptual RNA-exosome therapeutic delivery workflow.
- Understand translational, safety, clinical, and regulatory challenges in RNA-exosome therapeutics.
- Develop research-oriented ideas for academic projects, proposals, and publications.