| Attribute | Detail |
|---|---|
| Format | Online (e-LMS) |
| Level | Advanced |
| Duration | 3 Weeks |
| Certification | e-Certification + e-Marksheet |
| Fee | ₹5499 / $59 |
| Tools | Bioinformatics for CRISPR CRISPR Technology CRISPR Therapeutics CRISPR-Cas CRISPR-Cas in Agriculture |
About the CRISPR-Cas Genome Editing: Mechanisms and Applications Course
The CRISPR-Cas Genome Editing: Mechanisms and Applications course is an intermediate-level program designed to introduce learners to the principles, mechanisms, workflows, and real-world applications of CRISPR-Cas genome editing. The course explains how CRISPR-Cas systems are used to make precise genetic modifications and how this technology is transforming biotechnology, medical research, agriculture, therapeutics, and life sciences.
This program provides a structured understanding of CRISPR biology, guide RNA design, Cas enzymes, genome targeting, gene knockout, gene correction, gene regulation, and experimental planning. Learners will explore how CRISPR technology is applied in disease research, therapeutic development, crop improvement, functional genomics, and advanced biological research.
Special focus is given to Bioinformatics for CRISPR, CRISPR Technology, CRISPR Therapeutics, CRISPR-Cas, and CRISPR-Cas in Agriculture, helping learners understand both the scientific foundations and application potential of modern genome editing.
Program Highlights
• Mentorship by industry experts and NSTC faculty
• Structured learning in CRISPR-Cas mechanisms, genome editing workflows, and applications
• Hands-on conceptual exposure to guide RNA design and bioinformatics-based CRISPR planning
• Case studies on CRISPR therapeutics, disease modeling, and agricultural biotechnology
• Practical understanding of CRISPR-Cas systems for research, healthcare, and crop improvement
• Focus on ethical, safety, regulatory, and translational challenges in genome editing
• e-Certification + e-Marksheet upon successful completion
Course Curriculum
Module 1: Introduction to CRISPR-Cas Genome Editing
- Overview of Genome Editing and Its Importance
- History and Discovery of CRISPR-Cas Systems
- Basic Principles of CRISPR-Mediated Genetic Modification
- Applications of CRISPR in Biotechnology, Medicine, and Agriculture
Module 2: Biology and Mechanisms of CRISPR-Cas Systems
- Natural Role of CRISPR-Cas in Bacterial Immunity
- Structure and Function of CRISPR Arrays, Guide RNA, and Cas Proteins
- DNA Recognition, Target Binding, and Cleavage Mechanisms
- Types of CRISPR-Cas Systems and Their Research Importance
Module 3: CRISPR Technology and Experimental Design
- Core Components of CRISPR Genome Editing Experiments
- Guide RNA Design and Target Site Selection
- Gene Knockout, Gene Knock-In, and Gene Correction Strategies
- Planning CRISPR Experiments for Reliable Editing Outcomes
Module 4: Bioinformatics for CRISPR
- Role of Bioinformatics in CRISPR Target Selection
- Guide RNA Design, Specificity, and Efficiency Analysis
- Off-Target Prediction and Genome-Wide Screening Approaches
- Data Interpretation for CRISPR-Based Research Workflows
Module 5: CRISPR-Cas Applications in Biomedical Research
- CRISPR for Functional Genomics and Gene Function Studies
- Disease Modeling Using CRISPR-Based Editing
- Applications in Cancer, Genetic Disorders, and Infectious Disease Research
- CRISPR-Based Screening for Drug Discovery and Target Validation
Module 6: CRISPR Therapeutics
- Principles of CRISPR-Based Therapeutic Development
- Gene Correction for Inherited and Rare Diseases
- Ex Vivo and In Vivo Genome Editing Approaches
- Challenges in Delivery, Safety, Efficacy, and Clinical Translation
Module 7: CRISPR-Cas in Agriculture
- CRISPR Applications in Crop Improvement
- Genome Editing for Yield, Nutrition, Stress Tolerance, and Disease Resistance
- CRISPR-Based Approaches for Sustainable Agriculture
- Regulatory and Acceptance Challenges in Agricultural Genome Editing
Module 8: Ethics, Safety, and Future Opportunities in CRISPR
- Ethical Considerations in Human Genome Editing
- Biosafety, Off-Target Effects, and Responsible Research Practices
- Regulatory Considerations for CRISPR Therapeutics and Agricultural Applications
- Future Opportunities in Precision Medicine, Food Security, and Advanced Biotechnology
Tools, Techniques, or Platforms Covered
Bioinformatics for CRISPR CRISPR Technology CRISPR Therapeutics CRISPR-Cas CRISPR-Cas in Agriculture
Real-World Applications
- Developing CRISPR-based models for studying genetic diseases and biological pathways
- Designing guide RNA strategies for targeted genome editing experiments
- Supporting CRISPR therapeutics for inherited diseases, cancer research, and precision medicine
- Improving crop traits such as yield, nutrition, disease resistance, and climate resilience
- Using bioinformatics approaches to improve target selection and reduce off-target effects
- Applying CRISPR-Cas systems in biotechnology, pharmaceutical research, and agricultural innovation
- Exploring responsible and ethical use of genome editing technologies in research and industry
Who Should Attend & Prerequisites
- Designed for students, researchers, faculty members, laboratory professionals, biotechnology learners, healthcare research professionals, and industry participants interested in genome editing, molecular biology, biotechnology, therapeutics, and agricultural biotechnology.
- Suitable for learners from biotechnology, life sciences, genetics, molecular biology, biomedical science, microbiology, agriculture, bioinformatics, pharmaceutical science, and related fields.
Certification
